--- title: "Model overview" output: rmarkdown::html_vignette: toc: true number_sections: true bibliography: library.bib csl: https://raw.githubusercontent.com/citation-style-language/styles/master/apa-numeric-superscript-brackets.csl vignette: > %\VignetteIndexEntry{Model overview} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r, include = FALSE} knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) ``` # Introduction EpiNow2 provides several estimation models that can be combined for end-to-end epidemiological inference and forecasting. This vignette gives an overview of how these models connect. For a reference of what each model can do see the [model features](model_features.html) vignette. # Architecture The diagram below shows the main functions and how they relate to one another. ```{r architecture, echo = FALSE, out.width = "100%", fig.align = "center", fig.alt = "Diagram showing how the main EpiNow2 models connect."} knitr::include_graphics( "model-overview-architecture-1.png" ) ``` Data flows from top to bottom. Solid arrows show direct dependencies; dashed arrows show optional connections. Green boxes are options functions that configure the estimation models. See the [model features](model_features.html) vignette for what each function and option does. # Relationship between models `estimate_dist()` fits delay distributions from linelist data, accounting for double interval censoring and right truncation. Its output can define priors for the other models via `delay_opts()`, `gt_opts()`, or `trunc_opts()`. `estimate_truncation()` produces both a nowcast and a truncation distribution from multiple snapshots of the same data. The distribution is typically passed to `estimate_infections()` via `trunc_opts()` for truncation-adjusted inference, but can also be used via `delay_opts()` or `gt_opts()` where appropriate. `estimate_infections()` is the core model, estimating latent infections and the time-varying reproduction number from a count time series. Its posterior feeds into `forecast_infections()` for projections and can inform `simulate_infections()` for scenario analysis. Estimated primary observations from `estimate_infections()` are used as input to `estimate_secondary()`, which estimates secondary outcomes (e.g. deaths, hospitalisations). `forecast_secondary()` extends a fitted secondary model with new primary data; `simulate_secondary()` generates synthetic secondary observations. `epinow()` wraps `estimate_infections()` with logging and formatted output. `regional_epinow()` runs `epinow()` across regions in parallel. # Where to look next **Start here** - [Getting started](EpiNow2.html) — quick introduction and basic usage - [Model features](model_features.html) — feature reference for arguments and options **Model definitions** (mathematical detail) - [Infection model](estimate_infections.html) — `estimate_infections()` - [Gaussian process implementation](gaussian_process_implementation_details.html) — shared component used inside the renewal and back-calculation models - [Secondary model](estimate_secondary.html) — `estimate_secondary()` - [Truncation model](estimate_truncation.html) — `estimate_truncation()` - [Distribution model](estimate_dist.html) — `estimate_dist()` - [Understanding delay distributions](delays.html) — conceptual background on delays in _EpiNow2_ **Estimating the reproduction number** - [Workflow](estimate_infections_workflow.html) — end-to-end estimation and forecasting - [Configuration examples](estimate_infections_options.html) — different model configurations with results - [Prior choice guide](prior_choice_guide.html) — default priors and how to modify them **Auxiliary models** - [Fitting delay distributions](estimate_dist_workflow.html) — worked example for `estimate_dist()` - [Forecasting multiple data streams](forecasting_multiple_data_streams.html) — combining `estimate_infections()` with `forecast_secondary()` **Production use** - [epinow() and regional_epinow()](epinow.html) — wrappers for production runs **Case studies** - [External case studies](case-studies.html) — applications in the literature